FAPESP – São Paulo Research Foundation, Brazil
Job Information
Organisation/Company
FAPESP – São Paulo Research Foundation
Research Field
Chemistry
Researcher Profile
Established Researcher (R3)
Country
Brazil
Application Deadline
31 Mar 2024 – 23:59 (UTC)
Type of Contract
To be defined
Job Status
Not Applicable
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No
Job Description
A postdoctoral opportunity is currently available to investigate the biotechnological applications of bactericidal type IV secretion systems in Professor Chuck Farah’s laboratory at the Institute of Chemistry, University of São Paulo (IQ-USP), Brazil.
Bacteria utilize nanomachines to transfer macromolecules (such as proteins or DNA) across their cell envelope. Certain species within the Xanthomonadales, Burkholderales, and Neisseriales carry a specialized type IV secretion system (X-T4SS) designed to transport effector proteins (X-Tfes) into other Gram-negative species during interspecies conflict. Unraveling the molecular mechanisms governing substrate recognition by these secretion systems offers intriguing possibilities for their manipulation and the development of novel biotechnological tools for delivering engineered effectors against targeted pathogens.
Research will be conducted under the auspices of the Biology of Bacteria and Bacteriophages Research Center (CEPID B³), a São Paulo Research Foundation (FAPESP)-supported Research, Innovation, and Dissemination Center (CEPID) hosted by IQ-USP, led by Professor Chuck Farah.
Applicants must possess a PhD in Chemistry, Biochemistry, Biology, Physics, Biotechnology, Protein Engineering, or related fields. Prior experience in molecular biology, protein expression and purification, structural biology, and/or fluorescence microscopy is highly desirable.
Applications should be submitted until March 31, 2024, accompanied by:
– A short CV with a link to Google Scholar, ResearchID or ORCID profiles;
– A letter of motivation;
– Two letters of recommendation.
This opportunity is open to candidates of any nationality. The selected candidate will receive a FAPESP Post-Doctoral fellowship in the amount of R$ 9,047.40 monthly and a research contingency fund, equivalent to 10% of the annual value of the fellowship which should be spent on items directly related to the research activity.
More information about the fellowship is at: fapesp.br/oportunidades/6808 .
Requirements
Additional Information
Eligibility criteria
Eligible destination country/ies for fellows:
- Brazil
Eligibility of fellows: country/ies of residence:
- All
Eligibility of fellows: nationality/ies:
- All
Work Location(s)
Number of offers available1Company/InstituteInstituto de Química, Universidade de São Paulo (IQ-USP)CountryBrazilState/ProvinceSão PauloCitySão PauloPostal Code05508-000StreetAv Professor Lineu Prestes, 748Geofield
Where to apply
Website
http://www.fapesp.br/oportunidades/6808
Contact
State/Province
São Paulo
City
São Paulo
Website
http://www.fapesp.br/oportunidades/
Street
R. Pio XI, 1500 – Alto da Lapa
Postal Code
05468-901
