AbbVie is looking for a Sr. Scientist with a molecular biology and microbiology background to join their peptide display hit generation team. This role is responsible for leading and managing multiple technology development projects related to phage display of peptides for therapeutic discovery, including the generation of phage-display peptide libraries, screening against therapeutic targets, and identifying pharmaceutically relevant hits. This role will also utilize AbbVie’s proprietary peptide microarray platform to aid in accelerating hit identification from phage display campaigns
Responsibilities:
- Lead development of in-house peptide phage-display workflows that leverage a proprietary peptide microarray platform to accelerate hit identification. Includes design and generation of phage-display libraries, screening of peptide libraries against therapeutic targets, next-generation sequencing library preparation, and large-scale data analysis.
- Investigate state-of-the-art technologies for modifying peptide phage-display libraries using chemical modifications, non-canonical amino acid incorporation, etc.
- Efficiently analyze data from next-generation sequencing of phage libraries and other large-scale datasets.
- Routinely demonstrate scientific initiative and creativity in research or development activities.
- Performing laboratory research or method development.
- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drugs and radioactive compounds, GxP compliance, and animal care, where applicable.
Preferred Qualifications:
- Experience in peptide phage-display, including library design and generation, library screening, and data analysis
- Experience with generating next-generation sequencing libraries and analysis of resulting datasets
- Skills in coding for data science (e.g. Python) and/or a willingness to learn
Apply here https://careers.abbvie.com/en/job/sr-scientist-i-microbiology-in-madison-wi-jid-16390
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