Apply and develop advanced next-generation antibody engineering and cellular and molecular glycoengineering technologies to elucidate the role of glycosylation within complex immunological networks and diseases and to generate novel therapeutic approaches and drug candidates. Our main therapeutic interests are immuno-oncology, infectious diseases, and lung diseases. The focus lies within cellular engineering and glycoengineering of human innate immune cells using gene editing for highly effective cell-based immunotherapeutics and the design and development of their manufacturing processes.
Further focus areas are next-generation antibody engineering with bi-/ multi-specific and multimodal antibodies, phage display technologies, exosome engineering and drug delivery, gene therapy, NK—and DC-cell-based therapies, and their mammalian bioprocess engineering and manufacturing. We also have a strong focus on innovation and entrepreneurship.
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