This project aims to develop a minimal phage genome that can be used for biotech applications and to elucidate the function of phage genes. We will also develop a colorimetric-based selection technique for creating phage mutants. We will engineer phages that target different bacterial hosts to display different fluorescent proteins on the capsids. Finally, we will identify which genes are essential for phage SLUR96 infection.
Create phage mutants that encode putative anti-phage defense systems. Engineer phage SLUR96 to express putative anti-dense systems, then test these phages against strains of E. coli that express different anti-phage defense systems, to determine if these systems can be overcome. This is to be done in collaboration with researchers at Southampton University.
The University of Leicester will provide full overseas fee waivers for the duration of their study to all international students accepted at Leicester University.
Refer and apply here https://le.ac.uk/study/research-degrees/funded-opportunities/bbsrc-mibtp
For more phage-related research opportunities, click here https://jobs.thephage.xyz/
