Cystic fibrosis is the most common, genetically inherited disease in the UK and there are over 11,000 people living with this in the UK. Maintaining lung health throughout the life-course is a key priority for people with cystic fibrosis (pwCF). Lung infections are a major cause of morbidity and mortality in pwCF.
Bacteriophage (phage) therapy is safe and has the potential to be relatively easily adapted across different bacterial species. Chronic lung infections in pwCF have been treated and, in some cases resolved, using phage therapy.
In this project, students will design optimised phage cocktails that are active against clinically relevant, biofilm-growing bacteria in a mucin and DNA-rich environment with altered oxygen availability.
This PhD student will join a vibrant lab at the University of Liverpool and be part of a cohort of students, many funded by the TRAILFINDER Hub. Applications should be made to Prof Jo Fothergill ([email protected]) and include a CV and cover letter with the subject heading “Phage PhD Application”.
Applications are open to UK students only.
Click here for more such phage-related research opportunities https://jobs.thephage.xyz/
