This is a collaborative project between the Szczelkun lab (Bristol) and the Westra lab (Exeter). Work together with a collaborative team from the Universities of Bath, Bristol, Durham, Exeter, Liverpool, Manchester, and St. Andrews, funded as part of a BBSRC sLoLa grant, and study a newly identified bacterial defense.
To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. This novel innate immune system appears to use epigenetic modifications to prevent auto-immunity, like RM enzymes. The system can work in synergy with CRISPR-Cas systems when preventing phage infection
To apply, follow the link https://www.bristol.ac.uk/study/postgraduate/apply/start-application/
For more phage-related research opportunities, click here https://jobs.thephage.xyz/
