Two postdocs in computational biology of bacteria-phage co-evolution

The university of  Jagiellonian University (UJ) is seeking two motivated people to join our group as postdoctoral researchers, working on the computational biology of bacteria-phage co-evolution. The successful candidates will join the Microbial Genomics Group at Malopolska Centre of Biotechnology, Jagiellonian University in Krakow, Poland. Both positions are funded by the National Science Centre Poland.

The broad vision of the Microbial Genomics Group is to use computational biology, coupled with experimental data, to improve our understanding of the co-evolutionary process between the opportunistic bacterial pathogens, like Klebsiella pneumoniae, and its bacteriophages. The group is particularly focused on interactions between bacterial surface sugars (e.g., capsules) and phage receptor-binding proteins (e.g., tail fibres). They want to understand the role of co-evolution in shaping the genetic and phenotypic diversity of both bacteria and phages and build computational models to predict their interactions. They believe that doing so would bring us closer to using phages and phage-derived tools to combat the increasingly common infections by antimicrobial resistant bacteria.

The first postdoc position (OPUS postdoc) is focused on studying the evolution of the phage proteome. The successful candidate will compare the genetic, functional and structural similarity of millions of phage proteins and use evolutionary genomics and structural bioinformatics to better understand how phages evolve, from domains to proteins to genomes to populations. You can read more about this position here.

Click Here

The second postdoc position (Sonata Bis postdoc) is focused on reconciling co-evolutionary dynamics of bacterial surface sugars and temperate phages in bacteria of the Klebsiella genus to predict specificity of receptor-binding proteins in silico. To do so, the successful candidate will work with large collections of bacterial genomes and develop phylogenetic models of co-evolution between bacteria and their mobile genetic elements. You can read more about this position here.

Click Here

Both successful candidates will enjoy an international, interactive and supportive working environment of the rapidly growing bioinformatics environment at Malopolska Centre of Biotechnology, with frequent interactions with Structural and Functional Genomics Group and Bioinformatics Research Group. The candidates will collaborate with the world’s top research groups in UK, France and Australia and publish in top tier journals. They also will receive mentoring from senior peers as well as an opportunity to develop their own, independent research projects that align with the group’s interests.

Post a Comment

New comments are not allowed.*

Previous Post Next Post